Regina Peldszus is interested in human-technology interaction issues in high-reliability and safety-critical domains, predominantly space. This includes organizational characteristics, policy, and governance of complex large-scale sociotechnical systems including multilateral infrastructure; resilience and tacit operational practice in critical and routine scenarios; and transfer of good practice between different domains (space, nuclear, polar). From 2013 to 2015 she was an Internal Research Fellow and then external consultant at the European Space Agency, based in the Studies & Special Projects Division at the European Space Operations Centre (ESOC). In 2016, she joined the department of Space Situational Awareness at the German Aerospace Center (DRL) Space Administration, working on European space policy in the area of Space Situational Awareness.

Regina has contributed to human-systems integration projects in the European, Russian, and US space sector
. She is a member of the AIAA, the IFIP TC13 Human Computer Interaction (WG 13.5 Resilience, Reliability, Safety and Human Error in System Development), and the trilateral (ESA/ CNES/ DLR) Steering Group on Human Dependability.

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